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Treatment-Resistant Depression / Bipolar Clinic

The London Psychiatry Centre / Treatment-Resistant Depression / Bipolar Clinic

Did you know that the majority (52% or more) of people diagnosed with depression in the U.K. actually have undiagnosed subthreshold bipolar disorder but are considered to have treatment-resistant depression?

The first step in the management of TRD is to reconsider the diagnosis even before giving rTMS or any other treatment, because bipolar disorders are very often misdiagnosed as treatment-resistant depression.

Bipolar disorder is an illness which greatly impacts quality of life. It carries a high depression burden, considerable suicide rate (18%), an early death by 10 years from heart disease in 4/10, and has a very severe impact on relationships. But our bipolar clinic is here to help you get your life back.

A World Health Organisation (WHO) study found that over a lifetime, the level of disability in bipolar spectrum disorder is greater than all forms of cancer, epilepsy, and all known neurological diseases, including Alzheimer’s disease.

Traditionally, treatment for bipolar disorder involves a combination of three to four drugs which come with considerable side effects. However, a new treatment combination, pioneered by The London Psychiatry Centre, ensures the patient experiences minimal – if any – side effects. Our treatment protocol is patented and available exclusively at The London Psychiatry Centre.

Who Is It For?

This treatment will change the lives of those who suffer with mood disorders, including mixed, hypomanic and depressive phases of bipolar I, II, subthreshold bipolar, and depression with racing/crowded thoughts and/or agitation.

This groundbreaking discovery is big news and could lead to a global change in how bipolar sufferers are treated.


with our treatment programme (compared to 41.8% remission with traditional treatment)

The results were described as “life changing” by patients, and this was commented on by the Care Quality Commission (CQC) on page 8 of their report on the centre.

Patients treated at The London Psychiatry Centre, using a combination of rTMS and high-dose thyroid hormones, have recovered after years of unsuccessful treatment with drugs.

+ - What impact does bipolar disorder have on sufferers and their families?

It has been shown that bipolar disorder runs in families, with heritability estimates ranging between 80 to 90%. However, most people who have a relative with bipolar disorder will not develop the condition. Genetic factors have a stronger influence on the onset of bipolar disorder, but environmental factors such as the consumption of drugs and alcohol, poor sleep, stress and head injuries may trigger symptoms.

Family members may find it difficult to support a relative with bipolar disorder due to the mental anguish of seeing a loved one suffering, and the impact that this can have on their own mental health. There may also be financial implications when becoming responsible for a relative with the condition. However, with the right support and treatment, the situation can become easier to manage over time.

Most commonly, bipolar develops between ages 15-19, though many others experience the onset in their twenties. Our published sample of adults treated showed an age of onset range between 7-44 years of age.

+ - What is our treatment programme?

Our treatment programme gives patients their lives back – with a 96.4% remission rate. The treatment involves a combination of precision medicine, mitochondrial treatment, High-Dose Levothyroxine (HDL), and non-invasive treatment rTMS (Repetitive Transcranial Magnetic Stimulation). Find out more about our treatment programme here.

+ - What makes our treatment programme different from traditional treatment?

Simply put, our programme gets better results than traditional treatment.

With traditional treatment there is:

With our programme there is:

  • 96.4% recovery rate in a study including all three types of bipolar disorder (treatment-resistant bipolar disorder I, II, subthreshold, rapid cycling, and depression with agitation and racing thoughts whether it alternates or not with periods of flat depression with lethargy)

Read more about the differences.

+ - What are the types of bipolar disorder?

Our treatment programme can be used to treat all types of bipolar disorder. There are three common types: bipolar type I, bipolar type II, and subthreshold bipolar disorder.

Bipolar type I, the classic type, is characterised by a minimum of 7 days of mania and 2 weeks of depression. Those with bipolar type I have had at least one period of mania in their life.

Bipolar type II is characterised by minimum periods of 2 weeks of depression and 4 days of hypomania, a lesser form of elevated mood without periods of full-blown mania.

Subthreshold bipolar disorder or unspecified bipolar disorder – will present with symptoms of mania, depression and mixed states but will not meet the duration criteria of 7 days/2 weeks of Bipolar I and 4 days/2 weeks of bipolar II disorders. Symptoms can be as short as minutes to 3 days.

Read more about the types of bipolar disorder.

With our ground-breaking treatment programme, patients are getting their lives back. If you have any questions or would like to book in, please call us on 020 7580 4224 and we’ll be happy to help.

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